Mayweather has been involved in seven alleged instances of physical assault against five different women.
In 2012, the pound-for-pound best fighter in the world spent two months in a Nevada detention facility for an attack on Josie Harris, who is the mother of three of his four children.
And that marred past is something that Pacquiao feels very strongly about and is motivating him ahead of the fight.
Pacquiao is a congressman in the Philippines and it is one of the major problems that he hopes to have a positive impact on in his homeland.
Speaking to USA Today, Roach said: "Manny is really against domestic violence. It is a big issue maybe in the Philippines for him and being a congressman he can control some of that stuff.
"That is a big plus for me that Manny does not like the guy, I think the killer instinct is going to come back a lot faster."
Roach also says that this is the first time since working with Pacquiao that he can sense that his man does not like his opponent.
Pacquiao will face off with Mayweather in La Vegas on May 2 and it is a fight which will very much be 'good vs evil', according to Roach.
Roach himself is also a staunch activist against domestic violence.
"For the first time in my life with Manny Pacquiao, this is the first fighter he hasn't liked. I can tell."
Earlier this week, it was reported that money man Mayweather will wear a custom mouthguard worth $25,000 for the fight.
Mayweather is still considered the favourite for the win by the bookmakers.
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